SCSI2SD FAQ
From code/src wiki
Does SCSI2SD work with samplers ?
There are compatibility issues with the Akai MPC3000, most other samples should work ok.
Thanks to Carl at Precious Sound for putting in the time to test SCSI2SD.
Does SCSI2SD support 256 bytes-per-sector ? More than 512 bytes-per-sector
Yes, from firmware version 3.3, set via the scsi2sd-config utility.